Careers
Current job opportunities are listed below.
General Info
info@bryetpharma.com
2450 Holcombe Blvd.
Suite 1520
Houston, Texas 77021
USA
Research Scientist / Senior Scientist – Composite Drug Formulation and Chemistry
This is a full-time, onsite position located in Houston, TX. Interested applicants may apply on LinkedIn or contact us at info@bryetpharma.com.
Position Summary
We are seeking a skilled and motivated Research Scientist or Senior Scientist to join our composite drug R&D team, with a focus on the formulation and process development of novel nanoporous silicon microparticle (NSMP)-based composite drugs. This role is central to our translational strategy of designing and producing robust, scalable composite drugs that are aligned with CDMO practices for seamless tech transfer. The successful candidate will have a strong background in formulation and materials chemistry as well as advanced analytical approaches.
Key Responsibilities
- Design and optimize NSMP composite drug formulations for
oncology applications, with attention to scalability and CDMO compatibility. - Develop, execute, and interpret material and chemical characterization studies of NSMP drugs using tools such as SEM,
LC-MS, NMR, FTIR, and particle sizing methods. - Design and lead iterative development cycles supported by rigorous metrology and rapid data feedback.
- Author experimental protocols, technical reports, SOPs, and
documentation to support preclinical development and tech transfer. - Collaborate with cross-disciplinary teams in engineering, chemistry, biology, and external manufacturing partners.
- Other key duties relate to composite drug formulation studies that align with the company’s mission.
Qualifications
Required:
- PhD in Pharmaceutical sciences, Chemistry, Materials Science,
Biomedical Engineering, or a related discipline; or MS with 5+ years of relevant experience in industry or translational research. - Demonstrated hands-on experience with particle-based formulations.
- Expertise in analytical characterization involving one or more of SEM, LC-MS, and NMR.
- Proven ability to troubleshoot formulation and material performance challenges.
- Excellent written and oral communication skills, with attention to scientific rigor and documentation.
Preferred:
- Experience working with or transferring technology to CDMOs.
- Familiarity with QbD and process development under GMP or
regulatory-aligned environments. - Understanding of structure–function relationships in porous or
structured particulate carriers. - Experience in synthetic and/or conjugation chemistry.
- Prior involvement in IND-enabling studies or preclinical drug
product development. - Experience in cell culture and basic cell assays (viability, cell
uptake, etc.). - Experience in preclinical animal model studies.
- Located in commutable distance to Houston, Texas, United States
What We Offer:
- A mission-driven environment focused on transforming drug delivery with novel particle technologies.
- The opportunity to build translationally relevant novel composite drug platforms from the ground up.
- Competitive compensation package.
- Access to specialized equipment and local academic and industry partnerships for extended preclinical investigation capabilities.
Benefits
- Competitive medical, dental, and vision insurance with contribution by company
- Paid time off: 160 hours accrued annually
- Opportunities for professional development and advancement
BrYet US, Inc. may provide relocation assistance to the selected
candidate(s) if all preferred requirements are met.
BrYet US, Inc. is an equal opportunity employer, and we value diversity at our company. We encourage applications from all qualified candidates.
Research Scientist / Associate Scientist – Preclinical Studies of Novel Composite Drugs
This is a full-time, onsite position located in Houston, TX. Interested applicants may apply on LinkedIn or contact us at info@bryetpharma.com.
Position Summary
BrYet US, Inc. is seeking a motivated and skilled Research Scientist / Associate Scientist to join our oncology composite drug R&D team. This intermediate-level role is ideal for someone with strong technical expertise in cell biology and pharmacology, combined with a working knowledge of in vitro and in vivo preclinical studies. The successful candidate will contribute to in vitro assay development and pharmacology, design and execute small animal in vivo studies, and help advance nanoporous silicon microparticle (NSMP)-based platform in oncology and beyond. The role also includes contributing to scientific communications, including publications and presentations.
Key Responsibilities:
- Design and perform in vitro cellular and molecular assays to evaluate various NSMP composite drug activity and mechanism of action.
- Design and execute in vivo efficacy/safety and PK studies in small animals.
- Contribute to the development and refinement of in vitro and in vivo preclinical models relevant to oncology indications.
- Analyze and interpret experimental data; contribute to internal reports, regulatory documentation, and scientific publications.
- Present findings at internal meetings and support cross-functional research discussions.
- Provide scientific input on assay design, protocol optimization, and experimental strategy.
- Other key duties relate to preclinical studies that align with the company’s mission.
Qualifications
Required:
- M.S. or Ph.D. in Pharmaceutical Sciences, Cell Biology, Cancer Biology, or a related field.
- 3–5 years of post-degree experience in academic or industry research.
- Proficiency in cell-based assay development and cellular pharmacology studies.
- Familiarity with the design and interpretation of preclinical in vivo studies.
- Strong skills in data analysis, troubleshooting, and scientific communication.
- Ability to manage collaborations and work effectively in a fast-paced, team-oriented environment.
- Located in commutable distance to Houston, Texas, United States.
Preferred:
- Hands-on experimental experience with small animal studies (e.g., mice, rats).
- Experience working with or managing CROs or academic collaborators.
- Background in drug delivery systems and particulate formulations.
- Experience in oncology-focused drug discovery.
- Knowledge of tumor biology, resistance mechanisms, or drug mechanism of action studies.
- Experience contributing to peer-reviewed publications or scientific presentations.
What We Offer:
- A mission-driven environment focused on transforming drug delivery with novel particle technologies.
- The opportunity to build translationally relevant novel composite drug platforms from the ground up.
- Competitive compensation package.
- Access to specialized equipment and local academic and industry partnerships for extended preclinical investigation capabilities.
Benefits:
- Competitive medical, dental, and vision insurance with contribution by company.
- Paid time off: 160 hours accrued annually.
- Opportunities for professional development and advancement.
Work Authorization
Applicants must be legally authorized to work in the United States on a full-time basis and must not require sponsorship for an employment visa.
BrYet US, Inc. may provide relocation assistance to the selected candidate(s) if all preferred requirements are met.
BrYet US, Inc. is an equal opportunity employer, and we value diversity at our company. We encourage applications from all qualified candidates.